Maternal and child blood group incompatibility hemolysis

Maternal and child blood group incompatibility hemolytic disease is a blood group immunological disease caused by incompatibility between the pregnant woman and the fetus. It can occur in the early stages of the fetus and the newborn. When the dominant antigen inherited by the fetus from the father is exactly what the mother lacks, this antigen can enter the mother through pregnancy and childbirth and stimulate the mother to produce immune antibodies. When this antibody enters the fetal blood circulation through the placenta, it can cause the red blood cells to agglutinate and destroy, causing immune hemolysis of the fetus or newborn. This has no effect on pregnant women, but sick children can die from severe anemia, heart failure, or nuclear jaundice due to the infiltration of a large amount of bilirubin into brain cells. Even if they survive, their nerve cells and intellectual development and motor functions will all affected.