Pediatric scleroderma

Scleroderma is a chronic connective tissue disease that is rare in childhood. It is also a rheumatic disease. Mainly manifested as fibrosis and sclerosis of the skin and internal organs, which can involve the skin, internal organs, muscles, bones and joints. Its pathological features are connective tissue fibrosis, sclerosis, and occlusive arterioarteritis, with extensive arteriolar spasm . It can be divided into two types: localized scleroderma and systemic sclerosis (SSc). The former is mainly limited to skin thickening and fibrosis, while the latter, in addition to diffuse skin thickening and fibrosis, internal organs such as the heart, lungs, kidneys and digestive tract can also be violated. There is no essential difference between the two clinically and pathologically.