Anemia caused by excessive hemolysis

Hemolytic anemia is anemia that occurs when red blood cell destruction accelerates and bone marrow hematopoietic function is insufficiently compensated. The average survival time of normal red blood cells is about 120 days, and the red blood cell survival time of hemolytic anemia is often shortened to less than 15-20 days, and the shortest is only a few days. Premature destruction of red blood cells can occur extravascularly or intravascularly. Extravascular hemolysis means that red blood cells are destroyed and destroyed after being swallowed by macrophages in the spleen and liver. Intravascular hemolysis is the rupture of red blood cells directly in the blood circulation, and hemoglobin is released into the plasma. When hemolysis increases, the bone marrow's hematopoietic function can be compensated without anemia. This condition is called compensatory hemolytic disease. However, if the bone marrow's hematopoietic function has been accelerated but is still slower than the rate at which red blood cells are destroyed, hemolytic anemia occurs.

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