Hereditary prothrombin deficiency

Hereditary prothrombin (coagulation factor Ⅱ) deficiency is one of the rarest hereditary bleeding disorders. Prothrombin deficiency can be divided into two categories: ① hypothrombinemia (type Ⅰ deficiency), with both antigen and activity It is characterized by reduction; ② abnormal prothrombinemia (type Ⅱ deficiency), which is characterized by normal or low normal antigen levels and reduced prothrombin activity.

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