Cranial suture closes prematurely

Skull craniosis accounts for about 38% of abnormalities in the skull, and its clinical manifestations are mainly deformed skulls of various shapes. Due to the premature closure of the cranial suture, the growth of the skull is restricted, hindering the development of the brain, which results in increased intracranial pressure. Patients may have exophthalmos, lower vision, eye movement disorders, disc edema or secondary atrophy, visual impairment or blindness. Some patients may have mental retardation, and symptoms such as headache, nausea, and vomiting may occur in the later stages. Some patients may experience seizures due to atrophy of the cerebral cortex. The clinical manifestations of craniocervosis can be divided into two major categories: skull deformities and secondary symptoms.

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