Maternal and child ABO incompatibility

Maternal and child blood group incompatibility is isoimmunization due to blood group inconsistency between the pregnant woman and the fetus. In 1938 Darrow recognized that fetal blood was the pathogenic antigen. The blood group antigen inherited by the father from the father is exactly what the mother lacks. This antigen enters the mother through the placenta, causing the mother to undergo the same kind of immunity, and the antibodies produced enter the fetus through the placenta, causing the fetal and newborn red blood cells to be destroyed. Hemolytic disease. This type of hemolytic disease occurs only in the fetus and early neonates, and is a very important cause of neonatal hemolytic disease. The cause is related to immunity and genetics, so it can be caused by several consecutive fetuses. The disease has no adverse effects on pregnant women. It can cause death of the fetus and newborns due to severe anemia, or bilirubin encephalopathy occurs when a large amount of bilirubin produced by hemolysis penetrates into brain tissue.

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