Serum lead (Pb)

The average lead (Pb) loading in adults is 121 mg. The digestive tract is about 10% of the lead taken from food and water. The blood lead content is susceptible to environmental pollution, as well as the amount of urine and kidney function, and thus the fluctuation is relatively large. Basic Information Specialist classification: growth and development examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Tips: Do not eat too greasy, high-protein foods the day before the blood draw; fasting after 8:00 pm; alcohol in the blood will directly affect the test results, so avoid drinking. Normal value Adult <1.93 μmol/L (<40 μg/dl). Children <1.45 μmol/L (<30 μg/dl). Clinical significance Increased in chronic lead poisoning, such as accidentally taking a large number of lead-containing proprietary Chinese medicines. High results may be diseases: children with lead poisoning, multifocal motor neuropathy matters needing attention First, the precautions before blood draw 1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. 2. After 8 pm on the day before the physical examination, fasting should be done to avoid affecting the detection of indicators such as blood glucose in the second sky. 3, should relax when taking blood, to avoid the contraction of blood vessels caused by fear, increase the difficulty of blood collection. Second, should pay attention after blood draw 1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma. 2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended. 3, after the blood draw symptoms of fainting such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved. 4. If there is localized congestion, use a warm towel after 24 hours to promote absorption. Inspection process 1. Take an appropriate amount of blood and immediately send it for inspection. 2. Fluorescence spectrophotometric detection of erythrocyte protoporphyrin: Protoporphyrin (EP) is a fluorescent substance. The red blood cells were destroyed with an ethyl acetate-acetic acid mixed solution, the porphyrin was eluted, and the EP was extracted with hydrochloric acid, and the fluorescence peak was shown at 403 nm of the excitation light at 605 nm, which was quantified according to the fluorescence intensity. Not suitable for the crowd Inappropriate people: Generally there are no people who are not suitable. Adverse reactions and risks When blood lead is equal to or higher than 700μg/L, it may be accompanied by lead poisoning encephalopathy such as coma and convulsions.