recalcification time

The time of recalcification, that is, the time of plasma recalcification, is to re-add calcium in the plasma from which calcium is removed, and the endogenous coagulation process is reproduced. The difference between the specimen and the normal contrast is 40% larger than that of the normal control, and the abnormality can be considered as the endogenous coagulation system. An experimental examination of the defect, the anticoagulant plasma with sodium oxalate, the anticoagulant combined with calcium ions in the plasma and the blood coagulation process is interrupted. After the plasma is added with the appropriate calcium solution, the blood coagulation process continues to calcify. Normal human plasma recalcification time is within 3 minutes. Clinically, hemophilia, prothrombin, PTC, lack of fibrinogen deficiency or reduction of factor XII can cause prolonged plasma recalcification. Especially for the diagnosis of hemophilia has a certain significance. Basic Information Specialist classification: growth and development examination classification: blood examination Applicable gender: whether men and women apply fasting: not fasting Tips: Inform the doctor about the history of the drug and the medical history, and stop using the drugs that affect the test. Normal value 2.8 ± 0.5 (2.2 ~ 3.8) min. Clinical significance Abnormal results: Recalcification time prolongs VIII, IX, XI factor deficiency and severe deficiency of II, V, X factors, severe fibrinogen deficiency, and increased anticoagulant substances in the blood. The shortening of the recalcification time is seen in the hypercoagulable state. Need to check the crowd: Patients with abnormal blood anticoagulation time. High results may be diseases: disseminated intravascular coagulation in children, acquired circulatory anticoagulant syndrome, vitamin K deficiency, acquired circulating anticoagulant, disseminated intravascular coagulation, acquired vitamin K Abnormal clotting factor, disseminated intravascular coagulation in the elderly Requirements for inspection: (1) Blood should be taken smoothly, and there should be no hemolysis and blood clotting. (2) Immediately after taking blood, it should not be taken for a long time. (3) 0.025mol/L calcium chloride solution should be freshly prepared. (4) As a heparin monitoring index, sodium citrate should be used as an anticoagulant. (5) This test is slightly more sensitive than CT and can detect patients with factor VIII: C < 4%. Preparation before inspection: 1. Tell the doctor about the history of the medicine and the medical history. 2. Stop using the drugs that affect the test. Not suitable for people: There is no suitable crowd for the time being. Inspection process There are two ways: 1 surface glass dish method: This method is more sensitive than the test tube method, but not as simple as the test tube method. 2 test tube method: only use a test tube instead of a glass dish for testing. 2ml of venous blood was drawn, anticoagulated with citrate, and calcium was removed by chemical method to reproduce the endogenous coagulation process. The difference between the specimen and the normal control was 40% higher than that of the normal control, and the abnormality was determined. However, it is more sensitive, and some patients with mild hemophilia can be extended. Not suitable for the crowd No taboos. Adverse reactions and risks Subcutaneous hemorrhage: subcutaneous hemorrhage due to less than 5 minutes of compression time or blood draw technique.