nucleated red blood cells

It can not be seen in the peripheral blood of normal adults, and a small amount is seen in the peripheral blood of newborns within 1 week of birth. The appearance of nucleated red blood cells in adult peripheral blood is a pathological phenomenon. Basic Information Specialist classification: growth and development examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Normal value: no Above normal: negative: normal status. Positive: Common in proliferative anemia, erythroleukemia, pernicious anemia, cancer and other diseases. Tips: Pay attention to relaxation when taking blood. Normal value None (negative). Clinical significance Increase proliferative anemia, erythroleukemia, pernicious anemia, cancer. Positive results may be diseases: congenital erythropoiesis anemia, pediatric hereditary elliptic polycythemia, neonatal hemolytic disease considerations The immature red blood cells in the bone marrow of red blood disease and erythroleukemia are abnormally proliferated and released into the blood. The original red blood cells and early red blood cells are more common. When extramedullary hematopoietic bone marrow fibrosis, the spleen, liver, lymph nodes and other tissues restore the hematopoietic function during the embryonic period. These tissues have a large amount of immature blood cells entering the peripheral blood due to lack of ability to regulate blood cell release. Young red blood cells can be seen at various developmental stages, and immature granulocytes and megakaryocytes can be seen; others such as bone marrow metastasis and severe hypoxia. Inspection process 1. Take 1 tube and add 4ml of diluent. 2. Pipette 20 μl of peripheral blood with a calibrated micropipette. 3. Wipe off the external blood of the pipette, blow 20μl of whole blood into the diluent, and wash the remaining blood in the pipette with the diluent, and mix immediately. 4. Wipe the counting plate and the cover glass and cover the cover glass on the counting plate. 5. Drain the mixed red blood cell suspension into the counting chamber with a pipette. 6. After standing for 2 to 3 minutes, count the cells on the red blood cell line on the square of the central square and the five squares in the middle of the large square according to the principle of “no number, no number, no right”. . The count error of each square in normal blood is not more than 10. Not suitable for the crowd 1. Patients who have taken contraceptives, thyroid hormones, steroid hormones, etc., may affect the results of the examination and prohibit patients who have recently taken the drug history. 2, special diseases: patients with hematopoietic function to reduce disease, such as leukemia, various anemia, myelodysplastic syndrome, etc., unless the examination is essential, try to draw less blood. Adverse reactions and risks 1, subcutaneous hemorrhage: due to pressing time less than 5 minutes or blood draw technology is not enough, etc. can cause subcutaneous bleeding. 2, discomfort: the puncture site may appear pain, swelling, tenderness, subcutaneous ecchymosis visible to the naked eye. 3, dizzy or fainting: in the blood draw, due to emotional overstress, fear, reflex caused by vagus nerve excitement, blood pressure decreased, etc. caused by insufficient blood supply to the brain caused by fainting or dizziness. 4. Risk of infection: If you use an unclean needle, you may be at risk of infection.