Hepatitis B Virology Indicators

Hepatitis B virological indicators include hepatitis B virus "two pairs and a half", hepatitis B virus DNA, etc., to understand the virus replication and infectious size, is the most direct and specific indicator of hepatitis B infection. Hepatitis B virus DNA normal value quantitative test negative (less than normal value), indicating that hepatitis B virus replication is inhibited, replication is slow or even stop replication, blood HBV virus DNA content is low, hepatitis B virus DNA infection is weak. The normal value of HBVDNA test should be: <50U/ml. Basic Information Specialist classification: Infectious disease examination and classification: blood examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Normal value: no Above normal: negative: A negative result suggests no hepatitis B infection. Positive: A positive result suggests a hepatitis B virus infection or a hepatitis B antibody. Tips: Be careful not to take medication before checking. Normal value 1. In the two-to-half quantitative examination of hepatitis B, the normal value of two pairs of hepatitis B is 1HBsAg<0.5ng/ml (nng/ml) 2HBsAb<=10MIU/ml3HBeAg<=0.5PEIU/ml4HBeAb when HBeAb quantitative <=0.2PEIU/ ml5HBcAb <= 0.9 PEIU/ml. 2. Hepatitis B virus DNA normal value quantitative test negative (less than normal value), indicating that hepatitis B virus replication is inhibited, replication is slow or even stop replication, blood HBV virus DNA content is low, hepatitis B virus DNA infection is weak. The normal value of HBV DNA detection should be <50 U/ml. Clinical significance Abnormal result Hepatitis B two-and-a-half check "Hepatitis B big three positive" is positive for hepatitis B surface antigen, E antigen and core antibody. "Hepatitis B small three positive" is positive for hepatitis B surface antigen, E antibody and core antibody. Positive surface antigen indicates that it is infected by hepatitis B virus. It does not indicate the invasion of the virus. It does not indicate whether the lesion is a hepatitis B patient or a hepatitis B virus carrier. It only indicates that there is hepatitis B virus infection. If the E antigen is positive, plus the surface antigen is positive, the core antibody is positive, which is actually the big three yang. This indicates that the virus is actively replicating, and the hepatitis B virus in the blood is high in load and relatively contagious. If an E antibody is present, the virus replication is essentially static. However, in some patients with recurrent chronic hepatitis B, although hepatitis B surface antibody, E antibody, and core antibody were positive, there was still a replication of the hepatitis B virus. This group of people is contagious and needs antiviral treatment. Hepatitis B virus DNA normal value quantitative test positive (greater than normal value), indicating that hepatitis B virus replication is active, blood hepatitis B virus content is high, hepatitis B virus DNA is highly infectious, and the infectivity is proportional to the size of the value. Need to check the crowd: hepatitis B patients. Positive results may be diseases: metastatic liver cancer, hepatitis B virus precautions Taboo before inspection: 1. Be careful not to take the drug before the test, because some drugs will increase the burden on the liver, causing temporary damage to the liver function, which will lead to the accuracy of the liver function test results. 2. Pay attention to ensure adequate sleep before exercise, do not exercise vigorously, which may cause elevated transaminase, thus affecting the test results. 3. You must not drink alcohol the day before. Drinking alcohol will cause an increase in transaminase and affect the test results. Taboo when checking: 1. Can not eat before the examination, blood test requires fasting, fasting time is generally 8 to 12 hours. 2. The venous blood taken should be fresh and tested immediately. Inspection process 1. Two-and-a-half-test of hepatitis B: The patient's blood is taken, serum test is performed, and two antigens and three antibodies are detected. That is, HBsAg/anti-HBs, HBeAg/anti-HBe, anti-HBc. 2. The currently used hepatitis B virus DNA methods mainly include: fluorescent quantitative PCR technology, competitive PCR technology, PCR enzyme-linked immunosorbent assay, fluorescent labeled primer method and PCR enzyme-linked chemiluminescence method. Not suitable for the crowd 1. Patients who have taken contraceptives, thyroid hormones, steroid hormones, etc., may affect the results of the examination and prohibit patients who have recently taken the drug history. 2, special diseases: patients with hematopoietic function to reduce disease, such as leukemia, various anemia, myelodysplastic syndrome, etc., unless the examination is essential, try to draw less blood. Adverse reactions and risks 1, subcutaneous hemorrhage: due to pressing time less than 5 minutes or blood draw technology is not enough, etc. can cause subcutaneous bleeding. 2, discomfort: the puncture site may appear pain, swelling, tenderness, subcutaneous ecchymosis visible to the naked eye. 3, dizzy or fainting: in the blood draw, due to emotional overstress, fear, reflex caused by vagus nerve excitement, blood pressure decreased, etc. caused by insufficient blood supply to the brain caused by fainting or dizziness. 4. Risk of infection: If you use an unclean needle, you may be at risk of infection.