Intradermal test for paragonimiasis

The Pneumocystis intradermal test is an auxiliary test for the examination of blood-sucking worms. Intradermal injection with diluted adult fluke antigens can detect whether the patient has the corresponding antibody. If the skin test is positive, the patient has the possibility of infection with the paragonimiasis. This test can assist in the diagnosis of paragonimiasis and is used in epidemiological investigations. Through this examination, the corresponding symptoms can be judged. Basic Information Specialist classification: Infectious disease inspection and classification: pathogenic microorganism inspection Applicable gender: whether men and women apply fasting: not fasting Analysis results: Below normal: Normal value: no Above normal: negative: A negative test indicates that the body may not be infected with paragonimiasis. Positive: Positive test values ​​suggest that the body may have a paragonimiasi infection. Tips: Keep a normal diet and sleep. Normal value After the injection of the antigen for 15 minutes, the reaction was observed, and if there were papules and blush locally, the papule diameter was 13 mm and the blush diameter of 35 mm was negative according to the reaction size. 1. The papules have a diameter of 13 mm and the blush diameter of 35 mm is negative. 2. The diameter of the papules is 13mm-20mm, and the diameter of the blush is 35mm (+). 3. The diameter of the papules is 13mm-20mm, and the diameter of the blush is >35mm (++). 4. The diameter of the papules is 20mm or more, and the diameter of the red circle is 50mm (+++). 5. The diameter of the papules is more than 20mm, and the diameter of the redness is >50mm (++++). Clinical significance Abnormal results After 15 minutes of antigen injection, the reaction was observed. If there were papules and blush, the results were judged according to the reaction size. 1. The test results are positive, suggesting that the fluke is infected. 2. This test has a long duration of reaction. After 1 year of cure, it can still be positive, so this test can not be used as a standard for observing efficacy. 3. If the test and the control site are positive, it is a false positive. For other trematode diseases such as clonorchiasis, schistosomiasis, etc., may be incomplete cross-reaction. Population screening tests for the diagnosis and epidemiological investigation of paragonimiasis infection in populations in need of examination. Positive results may be diseases: paragonimiasis, brain trematode considerations Forbidden before examination: Maintain normal diet and sleep. Requirements for inspection: 1. The iodine traces for disinfection should be removed by deiodination with 75% ethanol to avoid affecting the skin test effect. 2. After 30 minutes of injection, the skin changes will begin to subside, and only the redness can be maintained for 24 hours. 3. If there is a serious systemic reaction, such as facial flushing, generalized itching, wheezing, palpitations or lymphangitis, symptomatic treatment such as desensitization and oxygen inhalation is needed. Oxygen should be prepared before the test to rescue drugs and equipment. Inspection process 1. Take the antigen of the larvae of the paragonimus adult larvae and dilute it to 1:2000 with 1:10000 thiomersal physiological saline. 2. After the forearm flexion was disinfected with iodine and ethanol, 0.1 ml of diluted antigen was injected into the skin. 3. In the same area or the same side of the opposite side of the distance of 10 cm, 0.1 ml of the same dilution of thimerosal chloride normal saline was injected intradermally as a control. Not suitable for the crowd Subjects with skin damage or other inflammatory reactions avoid this test. Adverse reactions and risks 1. Risk of infection: If you use an unclean needle, you may be at risk of infection. 2, the risk of allergies: the subject may be allergic to the injected antigen, or injected with contaminated antigen.