Cerebrospinal fluid cell count

Under normal circumstances, there are few cells in the cerebrospinal fluid, most of which are lymphocytes, a few are mononuclear cells, and occasionally neutrophils and eosinophils. However, under pathological conditions, cells in the cerebrospinal fluid can rapidly increase, and cells in various activated states appear. Cerebrospinal fluid cells are mainly derived from cells in the blood. Under pathological conditions, lymphocytes and mononuclear cells in the cerebrospinal fluid can still proliferate by self-cleavage. The direction of these cells in the cerebrospinal fluid is mainly drained through the lymphatic system, and degeneration and blood reflux are also one of the important destinations of cerebrospinal fluid cells. Basic Information Specialist classification: examination classification: cerebrospinal fluid examination Applicable gender: whether men and women apply fasting: fasting Tips: Cerebrospinal fluid specimens are sent for inspection immediately after collection. If they are placed for too long, the test results will be affected. Normal value Infant (0 ~ 20) × 106 / L (0 ~ 20 / mm3); Children (0 ~ 10) × 106 / L (0 ~ 10 / mm3); Adult (0 to 8) × 106 / L (0 ~ 8 / mm3). Clinical significance (1) Mild elevation of brain tumors, viral encephalitis, and meningitis. (2) moderately elevated central nervous system viral infection, central nervous system syphilis, tuberculous meningitis, and the like. (3) significantly increased purulent meningitis. High results may be diseases: arachnoiditis, cerebral schistosomiasis, congenital leukocyte granule syndrome in children, tropical spastic paraplegia, neonatal herpes simplex virus infection, Asperger syndrome, spinal cord compression considerations The cerebrospinal fluid specimens are sent for inspection immediately after collection. If they are placed for too long, the test results will be affected: if the cells are denatured and destroyed, the counting and classification will be inaccurate; some chemical substances such as glucose will reduce the decomposition content; the bacteria will cause autolysis to affect the detection rate of bacteria. . After the cerebrospinal fluid is extracted, three sterile tubes are generally divided. The first tube is used for bacterial culture, the second tube is used for chemical analysis and immunological examination, and the third tube is used for general traits and microscopic examination. The order of the three tubes should not be reversed. Due to the difficulty in collecting specimens, all inspection and testing procedures should be safe. Inspection process The mixed cerebrospinal fluid is directly dropped into the counting pool, and the total number of red and white blood cells in five large squares is multiplied by 2, which is the number of cells per microliter (μl), and then converted into the number of cells per liter of cerebrospinal fluid, and Reported. If the number of cells is large, count the number of cells in a large square × 10, that is, the total number of cells in the cerebrospinal fluid per microliter (μl), or dilute and count again by red blood cell counting. Not suitable for the crowd 1. If there is obvious papilledema or cerebral palsy, contraindications are contraindicated. 2. Patients who are in shock, exhaustion or endangered state and local skin inflammation, and lesions in the posterior cranial fossa are contraindicated. Adverse reactions and risks If the patient has symptoms such as breathing, pulse, or abnormal color during puncture, stop the operation immediately and deal with it accordingly.