Malignant eccrine poroma
Introduction
Introduction to malignant small sweat gland sweat tumor Malignanteccrineporoma (also known as perocarcinoma) occurs in long-standing small sweat glandular bronchoma (50%) but can also be primary. basic knowledge The proportion of illness: 0.015% Susceptible people: no special people Mode of infection: non-infectious complication:
Cause
The cause of malignant small sweat gland
(1) Causes of the disease
The etiology of this disease is not clear, and may have certain correlation with environmental factors, genetic factors, dietary factors, and mood and nutrition during pregnancy.
(two) pathogenesis
The pathogenesis is still unclear. Histopathology: In the adjacent side of benign small sweat gland, the interstitial cells have large and darkly stained irregular nucleus, and multinucleated cells are also visible. The cells are rich in glycogen and the malignant cells of the primary tumor. It can be limited to the epidermis or can be extended into the dermis. There are some free tumor cell islands in the dermis. Because there are many well-defined tumor cell nests in the epidermis, the epidermis often has considerable acanthal epithelial and dermal cells. The cystic cavity is visible.
Prevention
Malignant small sweat gland sweathole prevention
Pay attention to rest, work and rest, life in an orderly manner, and maintaining an optimistic, positive and upward attitude towards life can be of great help in preventing diseases.
Complication
Complications of malignant small sweat gland sweat pore tumor Complication
This disease generally does not have complications.
Symptom
Malignant small sweat gland sweat pore tumor symptoms common symptoms nodules
Similar to sweaty tumors, but can also be manifested as blue or black nodules, plaques or ulcerative tumors. More than 120 cases have been reported in the literature, with an average age of 70 years. The incidence of men and women is equal. The most common site of infection is calf (30%). , foot (20%), face (12%), thigh (8%), arm (7%), interesting is different from sweaty tumor, this disease rarely violates the palm (1 case) and the ankle (8 For example, about 20% of local metastases occur, and 10% of distant metastases occur. If metastasis occurs, the mortality rate is 70%.
Examine
Examination of malignant small sweat gland sweat pore tumor
Currently there are no related content description.
Histopathology: malignant small sweat gland sweaty canoma can be seen in the small sweat gland porokema or in the pure epidermis small sweat gland porokeoma adjacent.
In the benign small sweat gland, the perforated cells are seen in the adjacent cells. They have large and deep staining, irregular nucleation, and multinucleated cells. The cells are rich in glycogen. The malignant cells of the primary tumor can be limited to the epidermis or expandable. In the dermis, there are some free tumor cell islands in the dermis. Because there are many well-defined tumor cell nests in the epidermis, the epidermis often has considerable acanthosis, and the cysts are visible in the epidermis and dermal cell nests.
When the skin is metastasized, there are many tumor cell nests in the epidermis and dermis. The large and small tumor cell nests in the epidermis are surrounded by proliferating epidermal squamous cells, which are in the form of eczema-like cancer. In the lymphatic vessels, it is suggested that the tumor spreads in the lymphatic vessels of the skin. Due to the "epidermal nature" of the tumor cells, the tumor cells can invade the upper epidermis.
Diagnosis
Diagnosis and diagnosis of malignant small sweat gland sweat pore tumor
According to the clinical manifestations, the characteristics of skin lesions and histopathological features can be diagnosed.
Generally not confused with other diseases.
