folliculoma
Introduction
Introduction to hair follicle tumor Hair follicle tumor (trichofolliculoma), also known as hair follicle epithelial tumor or hair follicle sputum, is a benign tumor originating from hair follicle tissue, which occurs in the head and face. The skin lesions in the skin lesions are characterized by hair follicle tumors. The skin lesions of the skin lesions and the discharge of sebaceous substances are the characteristics of this disease, surgical resection is the main treatment. Multiple hair follicles are autosomal dominant, with a family history, but no single follicular tumor. basic knowledge The proportion of illness: 0.001% Susceptible people: no special people Mode of infection: non-infectious Complications: fibrous hair follicle tumor
Cause
Hair follicle tumor etiology
Genetic factors (75%):
The disease has a tendency to differentiate into hair. Multiple hair follicle tumors are autosomal dominant and have a family history, while single hair follicle tumors have no family history. The tumor is located in the dermis and is surrounded by connective tissue with clear boundary. A single cystic structure can be seen, which is filled with horny and sometimes visible hair shaft. Occasionally, 2 to 3 cystic structures are gathered together, and the cyst wall is keratinized. The squamous epithelium is connected to the epidermis. It can be seen that many epithelial tissues with bundle-like hyperplasia are radially arranged from the center of the cyst, and some form immature hair follicles. Sebum and small horny cysts can still be seen in the hyperplastic epithelial tissue.
Prevention
Hair follicle tumor prevention
You should first focus on and improve those factors that are closely related to our lives, such as quitting smoking, eating properly, exercising regularly, and losing weight. Appropriate exercise, enhance physical fitness and improve your disease resistance. Anyone who follows these simple and reasonable lifestyles can reduce their chances of developing cancer. Therefore, this disease cannot be directly prevented. Early detection, early diagnosis, and early treatment are important for preventing this disease.
Complication
Hair follicle tumor complications Complications
Often complicated by multiple fibrous hair follicle tumors.
Symptom
Hair follicle tumor symptoms Common symptoms The outer side of the eyebrows is sparse and the fine eyebrows become white nodules. The infiltrating tumors are hard hair follicles.
The disease can occur at any age, but mainly occurs in adults and usually has no symptoms.
1. Good hair: This disease occurs in the face, scalp and neck.
2. Clinical symptoms: manifested as papules with slightly higher skin surface on the face or head, top round nodules, central depression, nodules showing normal skin tone or reddish color, diameter generally around 4mm, small bundle slender and immature The hair is pierced from the central hole of the nodule, which contains black or white hair, which can discharge sebum-like substances and has a high diagnostic value, usually a single hair.
Examine
Hair follicle tumor examination
Histopathological examination showed a cystic structure filled with keratin. The wall of the capsule consisted of a keratinized stratified squamous epithelium. The epithelial tissue with a band of hyperplasia in the lumen was arranged radially from the center. The epithelial tissue was found to have sebum and small horny cysts. The dermis has a large cystic sac with a squamous epithelium. The horny horn is visible in the sac, and the double-folded hair shards are also common. In the case of a central hole, the large sac is continuous with the surface epidermis, indicating that the sac is Enlarged, distorted hair follicles, in some cases, there are 1 or 2 additional cysts in the dermis. From these "primary" hair follicle walls, many well-differentiated "secondary" hair follicles are emitted, and well-differentiated secondary hair follicles are common. Hairy nipples, often with outer and inner hair root sheaths, inner hair root sheath containing eosinophilic hair granules, fine hair in the center, small clusters of sebaceous gland cells embedded in the hair follicle wall, all hair follicle epithelial cords and secondary hair follicles Connected, these epithelial cords differentiated in the direction of the outer root sheath, so the surrounding cells are grid-like, and the cells are large and vacuolated due to glycogen.
Diagnosis
Diagnosis and identification of hair follicle tumor
According to the clinical manifestations, a single small dome-shaped nodule on the face or head, a small bundle of slender immature hair penetrating from the central hole of the nodule, combined with histopathology can be diagnosed.
Histological attention should be paid to the identification of hair blastoma, hair adenoma and basal cell carcinoma. Hair adenomas were first reported by Nikolowski in 1958. It happens in the face, followed by the buttocks. More common in adulthood. The lesion is a single solitary nodule with a proliferative or scorpion-like appearance with a diameter of 3 to 15 mm. Histopathology is a polygonal cyst.
