progressive muscle paralysis
Introduction
Introduction Acute poisoning, acute poisoning can occur when inhaling high concentrations of antimony dust. Other symptoms include nausea, vomiting, abdominal pain, diarrhea, slow pulse, progressive muscle paralysis, heart rhythm disorder, marked reduction in blood potassium, etc., which can be caused by heart rhythm disorders and respiratory muscle paralysis. Severe cases can be complicated by acute renal failure, hypoxic encephalopathy, acidosis and the like.
Cause
Cause
Metal bismuth is very toxic, but soluble strontium salts are highly toxic. The toxicity of different bismuth compounds is related to solubility, high solubility and high toxicity. Soluble cerium salts such as cerium chloride, cerium acetate and cerium nitrate are highly toxic. Sputum and compounds can enter the body through the respiratory tract, gastrointestinal tract and damaged skin. Inhalation of high concentrations of bismuth compound dust can cause acute poisoning. The absorbed strontium ions are rapidly distributed to muscles and bones within 24 hours. Barium salts have a strong and lasting stimulating effect on various muscles.
It excites the myocardium to increase myocardial stress and conductivity, and the heart beats faster. In severe cases, it can be converted to inhibit myocardial excitatory conduction, bradycardia, conduction block, severe ectopic rhythm and ventricular fibrillation and ventricular arrest. It can make the tracheal smooth muscle contract and even sputum, and also have excitatory effects on uterine smooth muscle, which can cause abortion, and can also cause salivation, vomiting, abdominal pain and diarrhea. At the same time, the muscle fibers are vibrated, convulsions, dyskinesias and limb paralysis, and severe cases are paralyzed. In addition, strontium may enhance the permeability of the cell membrane by means of calcium transfer or conversion of calcium, so that potassium ions enter the cell in a large amount, resulting in a decrease in serum potassium content and hypokalemia.
Examine
an examination
Related inspection
Electromyography muscle tension test
Other symptoms include nausea, vomiting, abdominal pain, diarrhea, slow pulse, progressive muscle paralysis, heart rhythm disorder, marked reduction in blood potassium, etc., which can be caused by heart rhythm disorders and respiratory muscle paralysis. Severe cases can be complicated by acute renal failure, hypoxic encephalopathy, acidosis and the like.
Diagnostic analysis was performed according to the medical history and the clinical manifestations of the patients.
Diagnosis
Differential diagnosis
Identification with scorpion poisoning. Early sputum poisoning is a symptom of the digestive tract. Symptoms of the nervous system can be seen later: lower extremities, especially foot hyperalgesia, are early manifestations of peripheral neuropathy in sputum poisoning, followed by typical multiple peripheral neuropathy. Metal cockroach poisoning is a poisoning reaction caused by the body's intake of strontium-containing compounds. The toxicity of cockroaches to mammals is higher than that of lead, mercury and other metal elements, which is equivalent to arsenic. The minimum lethal dose for adults is 12 mg/kg body weight, and for children 8.8 to 15 mg/kg body weight. Typical symptoms of sputum poisoning include hair loss, gastrointestinal reactions, and nervous system damage. The Mie line is usually left on the hand of the poisoned person. has strong accumulation toxicity, which can cause permanent damage to patients, including muscle atrophy, permanent damage of liver and kidney. Ingestion of bismuth compounds by the human body can be achieved by ingesting bismuth-containing compounds, drinking sputum-containing water sources, eating glutinous fruits and vegetables, and occupational exposure. Treatments for sputum poisoning include: use of Prussian blue, sodium dimercaptopropionate, sodium thiosulfate and other drugs to promote sputum ion excretion; oral potassium chloride solution to promote sputum metabolism; use diuretics to accelerate sputum excretion; use blood perfusion therapy Absorption of cesium ions and the like in vitro. Differential diagnosis should also pay attention to the exclusion of periodic paralysis, myasthenia gravis, progressive muscular dystrophy, peripheral neuropathy, acute multiple radiculitis.
Other symptoms include nausea, vomiting, abdominal pain, diarrhea, slow pulse, progressive muscle paralysis, heart rhythm disorder, marked reduction in blood potassium, etc., which can be caused by heart rhythm disorders and respiratory muscle paralysis. Severe cases can be complicated by acute renal failure, hypoxic encephalopathy, acidosis and the like. According to the above symptoms can be used as a basis for diagnosis.
