3.8sα2-glycoprotein

3.8S α2-glycoprotein is also called histidine-rich glycoprotein (HRG) because of its large number of histidine residues in its amino acid composition. It is mainly combined with heparin in the body and has a regulating effect on coagulation, fibrinolysis and immune function. In addition, it can combine a small amount of heme and bilirubin, which is a multifunctional protein. Synthesized in liver cells. HRG can be used as an indicator to monitor the occurrence and development of graft versus host. Animal tests suggest that HRG is a negative acute reactant.