Shrinking red blood cells

Shrinking red blood cells are a kind of red blood cell morphological changes caused by changes in external conditions. For example, when red blood cells are washed with physiological saline, the pH value is too high to cause morphological changes, or a small amount of oil is stained on the blood glass. The most severe shrinking cells look like Globulin and lightly shrunken cells can restore their inherent discoid morphology. Red blood cells also form shrinkage when the blood is left at 20 ° C overnight. Such abnormalities are common in patients with uremia.