Neutrophil chemotactic test

The phagocytosis of pathogens by neutrophils generally includes several steps including chemotaxis, conditioning, phagocytosis and sterilization, which is a very complicated process. Under the action of chemokines, neutrophils are directed to move around the bacteria. Bacteria that have been treated with opsonins tend to adhere to neutrophils, invade the neutrophil membrane, and swallow the bacteria to form them through the effect of puffing The phagosome is phagocytosed and fused with the lysosome in the cell to form a lysosome, killing the bacteria. However, if the body's chemokines are reduced or the phagocytic cells themselves do not respond to normal chemokines, it can lead to weakened phagocytic phagocytosis and make the body vulnerable to infection.