Cryptococcosis latex agglutination test

The latex agglutination test is a simple, fast and effective laboratory method for detecting cryptococcal infections. It uses latex particles as a carrier, and an anti-cryptococcus neonatal antibody is connected to the surface to form a sensitized latex suspension. For example, a specimen (serum, pleural effusion, bronchoalveolar lavage fluid, or cerebrospinal fluid) contains a certain amount of cryptococcal capsular polysaccharide Antigen can produce agglutination reaction particles visible to the naked eye. There is currently no established diagnostic threshold for this test, and its sensitivity and specificity have yet to be verified, but it provides useful clues for early diagnosis of pulmonary cryptococcosis.