Saliva-rich casein

Casein-rich protein is a family of phosphoproteins rich in tyrosine and proline in saliva, with a molecular weight of 5.38kD and an isoelectric point of pH4.22. Casein-rich can maintain saliva as a supersaturated calcium and phosphate solution. This saliva can prevent enamel demineralization, stimulate demineralized enamel remineralization, and gradually remineralize newly-grown teeth. If the activity of this acidic peptide is reduced, it may cause the calcium phosphate to precipitate and make calculus easy to form.