Serum anti-PreS2
The pre-S2 antigen in the serum of patients with acute hepatitis B induces the production of pre-S2 antibodies (Anti-PreS2) before the virus is eliminated, but there is no such special conversion in the process of chronicity, suggesting that this antibody may predict the recovery of HBV infection and Like -HBe, it is a marker of reduced viral replication.
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