Spinal muscular atrophy in children

Spinal muscular atrophy (SMA) is progressive spinal muscular atrophy, which is a type of muscle caused by degeneration of spinal anterior horn motor neurons and brainstem motor neurons. Weakness, muscular atrophy. It is an autosomal recessive genetic disease and is not uncommon clinically. According to the age of onset and the severity of myasthenia gravis, it is clinically divided into SMA-Ⅰ, SMA-Ⅱ, and SMA-Ⅲ types, namely infant, juvenile, and intermediate. The common feature is degeneration of spinal cord anterior horn cells. The clinical manifestations are progressive, symmetrical, and extensive flaccid paralysis and muscular atrophy, mainly on the proximal extremities. Intellectual development and feeling are normal. Different types are based on the age of onset, the rate of disease progression, the degree of muscle weakness, and the length of survival. So far, there is no specific effective treatment for SMA. The main treatment measures are to prevent or treat various complications caused by severe muscle weakness, such as pneumonia, malnutrition, skeletal deformity, mobility disorders, and psychosocial problems. The following highlights infantile spinal muscular atrophy.