Erythrocyte glucose phosphate isomerase

Red blood cell enzymes play an important role in regulating red blood cell metabolism. Deficiency of enzymes leads to reduced energy supply and shortened red blood cell life to cause hemolytic anemia. Most enzyme deficiency diseases are not caused by a lack of enzyme protein content, but are caused by enzyme protein deficiency (enzyme disease). Functional changes such as enzyme inactivation can quickly cause an equivalent amount of enzyme activity to decrease or lack. Most enzyme diseases are hereditary diseases. Acquired enzyme deficiency is non-specific and is associated with most hematological disorders.