Persistent low back pain with morning stiffness

Non-ocular clinical manifestations of ankylosing spondylitis scleritis: The most typical early manifestation is persistent low back pain (at least 3 months), which is unilaterally occult, blunt, or intermittent, with morning stiffness and reduced after activity . Ankylosing spondylitis scleritis (AS) is a chronic systemic disease of unknown origin, involving the spinal joints, sacroiliac joints, and tissues around the joints.