Transparent blisters of varying corneal size

The disease caused by bullous keratopathy is characterized by tarnishing of the corneal epithelium, transparent blisters of various sizes, and relapse after rupture. A state in which blisters are formed in the corneal epithelium is referred to as bullous keratopathy. Previously known as bullous keratitis. In fact, it is not an inflammation, but a degeneration. It is the result of abnormalities in the cortical layer, especially the endothelial layer, which causes water to be stored in the epithelial layer. Caused by abnormal or damaged corneal endothelial cells. The number of normal corneal endothelial cells is about 3000 cells / mm2, and the disease may occur when it is reduced to 500-1000 cells / mm2. After cataract surgery, ocular trauma, advanced glaucoma, severe uveitis, Fuch's corneal dystrophy, and corneal transplant failure can all cause destruction and reduction of corneal endothelial cells, leading to bullous corneal pathology.