Alcoholic gastric mucosal injury

Gastric mucosal damage can be induced when endogenous and exogenous damage factors such as ethanol, non-steroidal anti-inflammatory drugs (NSAID), acids, and bile reach a certain concentration or dose. Gastric mucosal damage is a programmed injury response: firstly, the superficial epithelium is shed to produce superficial mucosal damage; the damage develops further, and microvascular endothelial cell damage will cause mucosal ischemia, hypoxia, and tissue necrosis, leading to deep mucosa Injury (erosion or ulcer).