Hantavirus lung syndrome

Hantavirus pulmonary syndrome has an acute onset. At the beginning of the disease, there are prodromal symptoms such as chills, fever, myalgia, headache, and fatigue, as well as gastrointestinal symptoms such as nausea, vomiting, and diarrhea. The fever is generally 38-40 ° C. The above symptoms lasted for 12 hours, and the elderly reached several days. Most of them developed cough, shortness of breath, and respiratory distress quickly after 2 to 3 days. Some patients may have kidney damage. Prodromal, cardiopulmonary, and recovery periods. Since the outbreak of Hantavirus Pulmonary Syndrome (HPS), a major manifestation of acute respiratory failure, in the four corners of the border between the four continents of New Mexico, Colorado, Utah, and Arizona in the southwestern United States, there are currently 30 in the United States. Cases were found in all states. Cases of HPS have been reported in Canada, Brazil, Paraguay, Argentina, Chile, Bolivia, and Europe, Germany, the former Yugoslavia, Sweden, and Belgium. With the increase of HPS cases, various countries have carried out some research on this extremely fatal disease. It was found that in 1959, a patient consistent with the clinical manifestations of Hantavirus lung syndrome, and patients who recovered after treatment were detected with anti-SNV IgG antibodies at 1994 follow-up. Zaki et al. Carried out immunohistochemical examinations on autopsy tissues of 82 patients who died of noncardiogenic pulmonary edema before 1993, and found that 21 cases had Hantavirus antigen, which proved to be Hantavirus lung syndrome. The earliest case was 1978. In the onset of the disease, Hantavirus antigens were extensively deposited in endothelial cells in the same way as newly occurring HPS. In view of the fact that heart failure can occur in addition to pulmonary edema, North America and other countries also call this disease Hantavirus cardiopulmonary syndrome (HCPS). China is a high-incidence area of ​​Hantavirus infection, and it is worthwhile to be vigilant if it exists. A brief description of recent research abroad.

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