Tubule atrophy

Tubulotrophic lesions: Focal segmental glomerulosclerosis (FSGS) is a primary glomerular disease common in children and adults with nephrotic syndrome (NS). Histopathological features are segmental glomerular scars with or without foam cell formation and adhesion in the glomerular capillaries. Focal means that only part of the glomerulus is involved (involved glomeruli <50%); segmental means that some of the leaflets of the glomerulus are involved; spherical sclerosis refers to the hyaloid phase of the entire glomerulus Changes or scarring. The pathological features are often accompanied by tubular atrophy and renal interstitial fibrosis.