Beriberi

Athlete's disease is a deficiency of vitamin B1, which is a precursor of thiamine pyrophosphate (TPP). TPP is an important coenzyme in the decarboxylation reaction of pyruvate and α-ketoglutarate in the tricarboxylic acid cycle, and it is also a coenzyme of erythrocyte ketol transferase. In addition, there is a certain relationship between brain cell activity and nerve impulse transmission. Once lacking, it can cause a series of neurological and circulatory system symptoms called Beriberi.