Glanders

It is an infectious disease caused by Burkholderia gonorrhoeae. The horses, mules, and donkeys are a common infectious disease. Humans become infected due to contact with sick animals or items infected with pathogenic bacteria. The clinical manifestations are mainly acute fever, cellulitis, necrosis, abscesses, and granulomas appear in the respiratory tract, skin, and muscles. Some are chronic, with intermittent episodes, and the course of the disease can extend for several years. Aristotle recorded the disease in 330 BC, and named the disease in the Latin "Malleus" (malignant meaning). Apyrtos (375 AD) observed obesity in horses. Royer (1837) first described human glanders, Louml; ffer and Schütz (1882) first detected pathogenic bacteria from horses that died of glanders, and named the bacteria Pseudomonas mallei in 1985. It was listed in Burkholderia in 1993.