Acute posterior multifocal squamous pigment epithelial lesion

Acute multifocal posterior placoid pigment epitheliopathy (AMPPPE) was first reported by Gass in 1968 and has been continuously published in the literature. It is an inflammatory disease mainly occurring at the level of retinal pigment epithelium and choroidal capillaries. It is typically manifested by a sudden decrease in vision, varying in severity, and may also have deformed or dark spots (relatively dark spots in the center). Multiple yellow-white flat squamous lesions appear in the posterior pole. Inflammation is self-limiting, and vision recovery is fast. Most patients have good vision prognosis. About a third of patients had a history of colds before they became ill.