Leptospirosis

Leptospirosis (leptospirosis) is an acute systemic infectious disease caused by various types of pathogenic Leptospira (leptospira). It is a natural epidemic disease. Rats and pigs are the two main sources of infection. Leptospirosis spreads several continents in the world, especially in tropical and subtropical areas. The disease has been detected in 28 provinces, municipalities and autonomous regions in China, and the epidemic is more serious in Central South, Southwest, and East China. The clinical features are rapid onset, early symptoms such as high fever, general soreness, weakness, conjunctival congestion, gastrocnemius tenderness, and superficial lymphadenopathy. Leptotoxic blood symptoms such as superficial lymph node enlargement may be accompanied by pulmonary hemorrhage, diffuse pulmonary hemorrhage, myocarditis, and hemolysis. Target organ damage manifestations such as anemia, jaundice, systemic bleeding tendency, nephritis, meningitis, respiratory failure, heart failure; most cases recover in the late stages, and a few cases can occur with fever, ocular uveitis, and cerebral arterial occlusive inflammation. Complications associated with allergies after infection. Diffuse pulmonary hemorrhage, myocarditis, hemolytic anemia, and liver and kidney failure are common causes of death.