Neuronal tumors and mixed neuron and glial tumors

In 1993, the WHO classified neuroepithelial-derived tumors containing neuronal tumor cells into one category. In this type of tumor, including: 1. Small neuronal cell tumors include central neuroblastoma and olfactory neuroblastoma. 2. Large neuron cell tumors include ganglion cell tumors and Lhermitte-Duclos disease. 3. Neuron and glioma mixed tumors such as ganglioglioma and anaplastic ganglioglioma. 4. Although pineal glandular tumors have been classified into a separate category, they also belong to neuronal cell tumors. Gangliogliomas are rare tumors of the central nervous system and were first discovered and named by Courville in 1930. This tumor originates from embryonic undifferentiated cells and eventually differentiates into mature neuronal cells and glial cells. Due to the slow growth of the tumor, it was once classified as a hamartoma. At present, most authors believe that this is a benign mixed tumor with glioma cells and neuronal tumor cells. Cerebellar dysplastic ganglioblastoma (LDD) is a hamartoma-like lesion formed by the excessive proliferation of cerebellar ganglion cells instead of granulosa cells and Purkinje cells. By 2003, 140 cases were reported in the literature. The disease was reported by Lhermittle and Duclos in 1920. It is often referred to in the literature as LDD, also known as cerebellar hamartoma, Purkinje tumor, or benign hypertrophy of the cerebellum. The disease can occur at any age, mostly young and middle-aged, with an average age of 29 and 34 years. It has a long course and slow progress. The main symptoms are increased intracranial pressure, posterior cerebral nerve palsy and cerebellar damage signs.