Pediatric acute lymphocytic leukemia

Pediatric acute lymphoblastic leukemia (pediatric acute lymphoblastic leukemia) is the most common childhood neoplastic disease, which refers to malignant disease caused by clonal abnormal proliferation of precursor B, T or mature B lymphocytes. Acute lymphocytic leukemia accounts for 80% of childhood acute leukemia, with a peak incidence between 3 and 7 years. In the past 40 years, especially since the 1980s, great achievements have been made in the basic and clinical research of children's ALL. Children's ALL has become a curable malignant tumor. one. At present, the complete remission (CR) rate of pediatric ALL can reach more than 95%, and the continuous complete remission (CCR) rate of more than 5 years can reach 65% to 80%. The incidence of pediatric acute leukemia in China is about 1 in 100,000, of which total lymphocytic leukemia is the majority.