Proliferative vitreoretinopathy

Proliferative vitreoretinopathy (PVR) is the main reason for the failure of retinal retinal detachment reduction surgery. Its pathogenesis is caused by the contraction and stretching of extensive fibroproliferative membranes on the surface of the retina and behind the vitreous, causing retinal detachment. The fibrous proliferation membrane is mainly composed of pigment epithelial cells, glial cells, fibroblasts, fibroblasts, and macrophages. Pigment epithelial cells play an important role in the occurrence and development of proliferative vitreoretinopathy. It is not only the main cell for the formation and contraction of proliferative membranes, but also produces driving factors that attract fibroblasts and fibroblasts to participate in proliferative membrane Formation. Proliferative vitreoretinopathy has also been called extensive vitreous retraction (MVR), extensive preretinal retraction (MPR), extensive preretinal proliferation (MPP), and the like. PVR has been known for more than 100 years.