Lactic acidosis

Lactic acidosis (LA) is a rare and serious acute complication of diabetes. Once it occurs, the mortality rate can reach as high as 50%, especially blood lactic acid 25mmol / L, and the mortality rate can reach 80%. Plasma lactic acid concentration depends on glycolysis and lactic acid utilization rate. Tissue hypoxia, excessive lactic acid production due to various reasons, or decreased lactic acid utilization and elimination obstacles due to liver and kidney diseases will increase blood lactic acid concentration.