septicemia

Systemic infections caused by pathogenic bacteria that invade the blood circulation, grow and reproduce in them, and produce toxins, easily occur when the body's resistance is reduced. The main clinical manifestations are chills, high fever, symptoms of toxemia, rash, joint pain, hepatosplenomegaly, septic shock, and migrating lesions. Gram-positive cocci sepsis, Gram-negative bacillus sepsis, and sepsis sepsis. Most of them have an acute course, are severe, and have a poor prognosis. Today, it is further considered that sepsis is a series of chain reaction processes caused by pathogenic bacteria and their toxins and metabolites entering the bloodstream to activate and release inflammatory mesons. This process can clinically lead to dysfunction and failure of multiple organs throughout the body. That is, not only the presence of pathogenic bacteria in the body, but also the body's immune response and results. It is now known that the inflammation meson has complement components, arachidonic acid metabolites, tumor factors (TNF), interleukins (IL-s), interferons (IF-a), platelet activating factor (PAF), and Inflammatory cytokines (MPIC), proteases, thromboxane and oxygen free radicals. The main treatment is antibiotics, supplemented by other treatment methods. Preventive measures are to avoid damage to the skin and mucous membranes and prevent bacterial infections.