Hemoglobinopathy

Hemoglobinopathy is a group of hereditary blood diseases caused by abnormal molecular structure of hemoglobin (abnormal hemoglobin disease) or abnormal rate of synthesis of globin peptide chains (anemia of globin production, also known as marine anemia). Clinical manifestations of hemolytic anemia, methemoglobinemia, or cyanosis caused by hypoxia or increased red blood cells due to increased or decreased hemoglobin oxygen affinity.