Fuchs corneal endothelial dystrophy

Fuchs endothelial dystrophy, also known as cornea guttata, is a common phenomenon and its incidence increases significantly with age. In many patients with drip cornea, other aspects of the cornea are normal and do not affect vision. Corneal stroma and epithelial edema occur in a small number of patients and can cause significant loss of vision. Fuchs first described this clinical phenomenon in 1910, and later recognized that it is associated with primary corneal endothelial dystrophy, with changes in the corneal epithelium and stroma being secondary. There are three clinical types of primary corneal punctate turbidity: the first one is a number of degeneration points scattered behind the cornea, which are part of the normal senile changes in the endothelium; the second type, the number of degeneration is increased, often accompanied by endothelial pigment spots, fusion Film, simply called "endothelial dystrophy"; the third type, the number of degeneration is increasing, accompanied by corneal edema, which constitutes Fuchs endothelial dystrophy. Secondary keratosis occurs after corneal inflammation and is characteristic of syphilitic stromal keratitis.