Gardner syndrome

Gardner syndrome, also known as Weiner-Gardner syndrome, familial multiple colon polyp-osteoma-soft tissue tumor syndrome, familial colon polyposis. A chromosomal dominant inherited disease is a multifaceted manifestation of a single gene. In 1905, Gardner reported that colon polyposis and familial osteoma, soft tissue tumor, and colon cancer had more opportunities. Later, in 1958, Smith proposed the triad of colon polyp, soft tissue tumor, and osteoma as Gardner syndrome. The underlying pathogenesis is unknown. All colon polyps are adenomatous polyps with a canceration rate of 50%. Osteomas are benign. Both men and women can have the disease and have a family history.