Dialysis osteoarthropathy

Dialysis related arthropathy is one of the important complications of chronic dialysis patients. After the introduction of dialysis therapy in clinical medicine in the early 1960s, complications of rheumatism were quickly recognized. Caner and Decker reported acute arthritis and periarthritis in 1964, and later found that it was related to apatite crystals, and if hyperphosphatemia was adequately treated, its incidence would be reduced. Around 1975, Assenat discovered amyloid deposits in carpal tunnel tissue of patients on long-term dialysis. By 1985, Gejyo et al. Confirmed that the main component in this amyloid deposit was 2-microglobulin (2M), so it was called 2-microglobulin amyloidosis.