Pediatric autoimmune hemolytic anemia with thrombocytopenia syndrome

Autoimmune hemolytic anemia (AIHA) is a group of hemolysis produced by the destruction of self red blood cells due to the disorder of the immune function of the body, producing antibodies and / or complements to self red blood cells, adsorbing on the surface of red blood cells, causing red blood cells A type of hemolytic anemia caused by accelerated destruction. Some patients develop thrombocytopenia with increased antiplatelet antibodies (PAIg) during the course of the disease, called Evans syndrome, also known as Fisher-Evans syndrome, primary thrombocytopenic purpura with acquired hemolytic anemia. When the human immune surveillance function is abnormal and the red blood cell antigenicity is changed or foreign infections such as mycoplasma and red blood cells have the same antigenicity, autoantibodies will be produced. This disease is not uncommon in childhood, and its incidence accounts for about a quarter of all hemolytic anemia. 77% occur in children under 10, with slightly more men than women.