Acute infective endocarditis

Acute infective endocarditis (AIE) is mostly part of a severe systemic infection, and the pathogenic microorganisms are highly toxic, such as Staphylococcus aureus (most common, accounting for more than 50%), hemolytic streptococcus, meningitis Cocci and Escherichia coli. Clinically, it is rarer than subacute infective endocarditis, and patients have no history of heart disease. Acute infective endocarditis is mostly part of a severe systemic infection. Sudden onset and rapid progress. 60% of patients had no underlying heart disease, and the pathogenic bacteria had strong virulence. Staphylococcus aureus accounted for more than 50%. Hemolytic streptococcus, pneumococcus, gram-negative bacilli, and fungi can also cause disease. Septicemia is the main clinical manifestation, high fever, chills, tachycardia, shortness of breath, muscle and joint pain, disturbance of consciousness, skin petechiae, embolism of various organs, heart murmur changes, white blood cells significantly increase, progressive anemia, and positive blood culture Because of the severe symptoms of systemic infection, the clinical manifestations of acute infective endocarditis can be masked. If effective antibiotics are not used in a timely manner, the mortality rate is high.