Chronic myelogenous leukemia in children

Chronic myelogenors leukemia (CML) is the first blood cell disease to be recognized in leukemia, and its clinical manifestations and hematological examinations are unique. Chronic leukemia is rare in childhood, accounting for 3% to 5% of childhood leukemia, of which mainly chronic myelogenous leukemia. The disease is characterized by elevated white blood cells and splenomegaly, and presents with acute leukemia after sudden changes. The clinical and biological characteristics of CML in infants are significantly different from those of adult CML, so they can be divided into two types: adult and juvenile. The pathogenesis of CML is unknown, and it is generally believed that the disease is a pluripotent hematopoietic stem cell disease, and its occurrence is related to certain chemicals and genetic factors.