Pediatric Fibula Atrophy

Peroneal myoatrophy, also known as Charcot-Marie-Tooth disease (CMT), is a group of the most common familial peripheral neuropathy, accounting for about 90% of all hereditary neuropathies. The common characteristics of this group of diseases are the onset of children or adolescents, chronic progressive peroneal muscle atrophy, symptoms and signs are relatively symmetrical, and most patients have family history. This disease was first reported by Charcot, Marie, and Tooth in 1886, so it is also called Charcot-Marie-Tooth (CMT) disease. Because fibular muscle atrophy is the main clinical feature, it is also called peroneal myoatrophy. Although Dyck proposed the use of hereditary motor sensory neuropathy (HMSN) as the official name for this group of diseases, most literature is still used to CMT. According to neuroelectrophysiology and neuropathology, CMT is divided into type Ⅰ and type Ⅱ, type CMT Ⅰ is called hypertrophic type, and type CMT Ⅱ is called neuronal type.