Periodic hypokalemia in children

Periodic paralysis is a group of diseases characterized by repetitive, self-limited flaccid paralysis of skeletal muscle. According to the changes of serum potassium during its onset, it can be divided into three types of hypokalemia, hyperkalemia and normal potassium. Hypokalemic periodic paralysis is mainly characterized by paroxysmal flaccid paralysis of the skeletal muscle and a decrease in serum potassium during the episode. The disease is autosomal dominant, with incomplete penetrance, and sporadic cases can be seen. The disease gene is located in the long arm region of chromosome 1 (Iq3.1-3.2).