Soft spot urethra

Soft spot disease (malacoplakia) is a rare inflammatory disease. It was first reported by Michaelis and Gutmann in 1902. In 1903, von Hansemann named the disease as soft spot disease in the Greek malaco (soft) and plakia (plaque). Stanton and Maxted (1981) reviewed 153 patients. Soft spot disease occurs in 40% of the bladder, 11% of the ureter, 16% of the parenchyma of the kidney, and 16% of the posterior peritoneal cavity. Soft spots can also occur in other parts of the body, such as the genitals, gastrointestinal tract, skin, bones, and mesenteric lymph nodes. Patients with soft spot urinary system are often accompanied by chronic Escherichia coli.