Cryoglobulinemia renal damage

Cryoglobulin refers to a type of globulin that precipitates or jelly when the temperature of the plasma drops to 4-20 ° C. When the temperature rises to 37 ° C, it is dissolved again. Normal serum contains only a small amount of cryoglobulin. When its concentration exceeds 100 mg / L, it is called cryoglobulinemia. Those with elevated serum cryoglobulin are often accompanied by glomerular disease, which is called renal damage due to cryoglobulinemia.