Renal anemia in children

Renal anemia refers to anemia caused by inadequate production of renal erythropoietin (EPO) or toxic substances in plasma of uremia that interfere with the production and metabolism of red blood cells due to various factors. Although recent studies have learned that kidneys are closely related to the formation of red blood cells, there are still some debates about the mechanism of renal anemia. At present, it is generally believed that the occurrence of renal anemia is caused by multiple factors and comprehensive disorders. Severe kidney disease is associated with anemia when azotemia occurs. The degree of anemia has a parallel relationship with azotemia. Generally, anemia occurs when the glomerular filtration rate decreases to 25% to 30% of normal. Clinically, renal anemia can be divided into renal anemia with normal renal function and renal anemia caused by chronic renal failure. The latter is more common and is one of the important reasons for secondary anemia.