Renal damage

Monoclonal disease can be divided into primary monoclonal globulinopathy and secondary monoclonal globulinemia. Primary monoclonal globulin disease is a group of diseases characterized by the proliferation of monoclonal plasma cells. It refers to the presence of M protein in serum, but its importance is that MGUS sometimes progresses to monoclonal globulin disorders such as multiple bone marrow. Tumors (MM), primary amyloidosis and primary macroglobulinemia. Primary monoclonal globulinopathy can cause kidney damage.